A common vitamin could influence bathroom frequency

Scientists studying genetic data from over a quarter million people have uncovered new clues about what controls how fast the gut moves. They identified multiple DNA regions linked to bowel movement frequency, confirming known gut pathways and revealing new ones. The biggest surprise was a strong connection to vitamin B1, a common nutrient not usually linked to digestion.

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MRI scans show exercise can make the brain look younger

New research suggests that consistent aerobic exercise can help keep your brain biologically younger. Adults who exercised regularly for a year showed brains that appeared nearly a year younger than those who didn’t change their habits. The study focused on midlife, a critical window when prevention may offer long-term benefits. Even small shifts in brain age could add up over decades.

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A simple blood test mismatch linked to kidney failure and death

A major global study suggests that a hidden mismatch between two common blood tests could quietly signal serious trouble ahead. When results from creatinine and cystatin C—two markers used to assess kidney health—don’t line up, the risk of kidney failure, heart disease, and even death appears to rise sharply. Researchers found that this gap is especially common among hospitalized and older patients, and that relying on just one test may miss early warning signs.

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Scientists are building viruses from scratch to fight superbugs

Researchers from New England Biolabs (NEB®) and Yale University describe the first fully synthetic bacteriophage engineering system for Pseudomonas aeruginosa, an antibiotic-resistant bacterium of global concern, in a new PNAS study. The system is enabled by NEB’s High-Complexity Golden Gate Assembly (HC-GGA) platform. In this method, researchers engineer bacteriophages synthetically using sequence data rather than bacteriophage isolates.

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Tiny doses of THC show big benefits for HIV treatment

A new study suggests that micro-doses of THC could help counter many long-term side effects of HIV treatment without causing intoxication. In animal models, low-dose THC reduced inflammation, improved gut bacteria, boosted serotonin, and lowered harmful cholesterol and bile acids. Surprisingly, it also reduced circulating levels of antiretroviral drugs while maintaining viral suppression, potentially protecting the liver. Scientists say the results point to a promising new approach for managing chronic complications of HIV.

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A common painkiller may be quietly changing cancer risk

Ibuprofen may be doing more than easing aches and pains—it could also help reduce the risk of some cancers. Studies have linked regular use to lower rates of endometrial and bowel cancer, likely because the drug dampens inflammation that fuels tumor growth. Researchers have even found it can interfere with genes cancer cells rely on to survive. Still, experts warn that long-term use carries risks and shouldn’t replace proven prevention strategies.

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Major review finds no autism or ADHD risk from pregnancy Tylenol

A major new scientific review brings reassuring news for expectant parents: using acetaminophen, commonly known as Tylenol, during pregnancy does not increase a child’s risk of autism, ADHD, or intellectual disability. Researchers analyzed 43 high-quality studies, including powerful sibling comparisons that help separate medication effects from genetics and family environment. Earlier warnings appear to have been driven by underlying maternal health factors such as fever or pain rather than the medication itself.

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How cancer disrupts the brain and triggers anxiety and insomnia

Scientists have discovered that breast cancer can quietly throw the brain’s internal clock off balance—almost immediately after cancer begins. In mice, tumors flattened the natural daily rhythm of stress hormones, disrupting the brain-body feedback loop that regulates stress, sleep, and immunity. Remarkably, when researchers restored the correct day-night rhythm in specific brain neurons, stress hormone cycles snapped back into place, immune cells flooded the tumors, and the cancers shrank—without using any anti-cancer drugs.

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Scientists find ‘master regulator’ that could reverse brain aging

Researchers have identified OTULIN, an immune-regulating enzyme, as a key trigger of tau buildup in the brain. When OTULIN was disabled, tau vanished from neurons and brain cells remained healthy. The findings challenge long-held assumptions about tau’s necessity and highlight a promising new path for fighting Alzheimer’s and brain aging. Scientists now believe OTULIN may act as a master switch for inflammation and age-related brain decline.

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The real danger of Tylenol has nothing to do with autism

While social media continues to circulate claims linking acetaminophen to autism in children, medical experts say those fears distract from a far more serious and proven danger: overdose. Acetaminophen, found in Tylenol and many cold and flu remedies, is one of the leading causes of emergency room visits, hospitalizations, and acute liver failure in the United States.

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Scientists sent viruses to space and they evolved in surprising ways

When scientists sent bacteria-infecting viruses to the International Space Station, the microbes did not behave the same way they do on Earth. In microgravity, infections still occurred, but both viruses and bacteria evolved differently over time. Genetic changes emerged that altered how viruses attach to bacteria and how bacteria defend themselves. The findings could help improve phage therapies against drug-resistant infections.

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A 47-year study reveals when fitness and strength start to fade

A long-running Swedish study has followed adults for nearly five decades, uncovering when physical decline truly begins. Fitness and strength start slipping around age 35, then worsen gradually with age. The encouraging twist: adults who began exercising later still improved their physical capacity by up to 10 percent. It’s a powerful reminder that staying active matters, even if you start late.

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Researchers found a tipping point for video gaming and health

Moderate video gaming appears harmless, but heavy gaming may take a toll on young people’s health. Researchers found that students gaming more than 10 hours a week had worse diets, higher body weight, and poorer sleep than lighter gamers. Below that level, health outcomes were largely similar. The findings suggest balance, not abstinence, is key.

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Vitamin A may be helping cancer hide from the immune system

A vitamin A byproduct has been found to quietly disarm the immune system, allowing tumors to evade attack and weakening cancer vaccines. Scientists have now developed a drug that shuts down this pathway, dramatically boosting immune responses and slowing cancer growth in preclinical studies.

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Statins may help almost everyone with type 2 diabetes live longer

New research suggests statins may protect adults with type 2 diabetes regardless of how low their predicted heart risk appears. In a large UK study, statin use was linked to fewer deaths and major cardiac events across all risk levels. Even those labeled “low risk” benefited, challenging long-held assumptions about who should receive preventive therapy. Side effects were rare and generally mild.

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Northwestern Medicine’s new antibody wakes the immune system against pancreatic cancer

Pancreatic cancer uses a sugar-coated disguise to evade the immune system, helping explain why it’s so hard to treat. Northwestern scientists discovered this hidden mechanism and created an antibody that strips away the tumor’s protective signal. In animal tests, immune cells sprang back into action and tumors grew much more slowly. The team is now refining the therapy for future human trials.

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Massive brain study reveals why memory loss can suddenly speed up with age

A massive international brain study has revealed that memory decline with age isn’t driven by a single brain region or gene, but by widespread structural changes across the brain that build up over time. Analyzing thousands of MRI scans and memory tests from healthy adults, researchers found that memory loss accelerates as brain tissue shrinkage increases, especially later in life. While the hippocampus plays a key role, many other brain regions also contribute, forming a broad vulnerability rather than isolated damage.

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Millions with dementia still prescribed drugs linked to falls and confusion

Despite longstanding guidelines, many dementia patients are still prescribed brain-altering medications that can raise the risk of falls and confusion. A new study shows that while prescribing has decreased overall, people with cognitive impairment remain more likely to receive these drugs. In many cases, there was no documented medical justification. The results suggest that medication safety remains a serious concern in dementia care.

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This common dinner rule makes meals more awkward

Waiting to eat when your food arrives first feels polite—but it may be mostly for your own peace of mind. Researchers found people feel far more uncomfortable breaking the “wait until everyone is served” rule than they expect others would feel watching it happen. Even being told to go ahead doesn’t fully ease the discomfort. Serving everyone at once could reduce awkwardness and make meals more enjoyable.

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Why music brings no joy to some people

A small group of people experience no pleasure from music despite normal hearing and intact emotions. Brain imaging reveals that their auditory and reward systems fail to properly communicate, leaving music emotionally flat. Researchers developed a questionnaire to measure how rewarding music feels across emotions, mood, movement, and social connection. The findings suggest pleasure isn’t all-or-nothing and may depend on how specific brain networks connect.

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A little-known health syndrome may affect nearly everyone

Most U.S. adults have risk factors tied to a little-known condition called CKM syndrome, which connects heart disease, kidney problems, diabetes, and obesity into one powerful health threat. When these issues overlap, the danger rises far more than when they occur alone. Despite low awareness, people are eager to learn how CKM is diagnosed and treated. Experts say understanding how these systems work together could prevent serious, life-threatening events.

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A daily fish oil supplement slashed serious heart risks in dialysis patients

A new international trial has delivered striking results for people on dialysis, showing that daily fish oil supplements can sharply reduce serious heart-related events. Patients taking fish oil had far fewer heart attacks, strokes, and cardiac deaths than those on placebo. Researchers say this is especially important because dialysis patients face extreme cardiovascular risk and few proven treatment options. The findings mark a rare breakthrough in kidney care.

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Injection turns sleeping tumor immune cells into cancer fighters

KAIST researchers have developed a way to reprogram immune cells already inside tumors into cancer-killing machines. A drug injected directly into the tumor is absorbed by macrophages, prompting them to recognize and attack cancer cells while activating nearby immune defenses. This eliminates the need for lab-based cell extraction and modification. In animal models, the strategy significantly slowed tumor growth and sparked strong anticancer immune responses.

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A room full of flu patients and no one got sick

In a striking real-world experiment, flu patients spent days indoors with healthy volunteers, but the virus never spread. Researchers found that limited coughing and well-mixed indoor air kept virus levels low, even with close contact. Age may have helped too, since middle-aged adults are less likely to catch the flu than younger people. The results highlight ventilation, air movement, and masks as key defenses against infection.

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Scientists uncover a hidden aging program in the gut that fuels cancer risk

Although the gut renews itself constantly, its stem cells accumulate age-related molecular changes that quietly alter how genes are switched on and off. Scientists found that this “epigenetic drift” follows a clear pattern and appears in both aging intestines and most colon cancers. Some regions age faster than others, forming a patchwork of weakened tissue more prone to degeneration. Encouragingly, researchers showed this drift can be slowed—and partly reversed—by restoring iron levels or key cellular signals.

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Sleeping less than 7 hours could cut years off your life

Sleep isn’t just about feeling rested—it may be one of the strongest predictors of how long you live. Researchers analyzing nationwide data found that insufficient sleep was more closely tied to shorter life expectancy than diet, exercise, or loneliness. The connection was consistent year after year and across most U.S. states. The takeaway is simple but powerful: getting seven to nine hours of sleep may be one of the best things you can do for long-term health.

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A hidden loop is powering deadly pancreatic cancer

Pancreatic cancer is notoriously hard to treat, often resisting therapies that target its most common mutations. Researchers have now uncovered a hidden three-part loop that fuels tumor growth, involving the cancer drivers SRSF1, AURKA, and MYC. By targeting just one part of this loop with a specially designed molecule, they were able to shut down all three at once. The result was a dramatic loss of tumor cell survival, offering new hope for smarter, more effective treatments.

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Long COVID may be fueled by inflammation and tiny clots

Long COVID affects an estimated 65 million people worldwide and can damage the brain, heart, blood vessels, and immune system long after infection. Researchers now link symptoms to lingering virus, inflammation, micro-clots, and disrupted energy metabolism. While structured rehab and pacing can improve quality of life, a growing list of experimental treatments—from antivirals and metformin to microbiome therapies and biologics—shows early promise. Clear answers, however, are still limited by small studies and the lack of large, definitive trials.

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People in Brazil are living past 110 and scientists want to know why

Scientists are uncovering why Brazil may be one of the most important yet underused resources for studying extreme longevity. Its highly diverse population harbors millions of genetic variants missing from standard datasets, including rare changes linked to immune strength and cellular maintenance. Brazilian supercentenarians often remain mentally sharp, survive serious infections, and come from families where multiple members live past 100. Together, they reveal aging not as inevitable decline, but as a form of biological resilience.

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Just 10 minutes of exercise can trigger powerful anti-cancer effects

A brief, intense workout may do more than boost fitness—it could help fight cancer. Researchers found that just 10 minutes of hard exercise releases molecules into the bloodstream that switch on DNA repair and shut down cancer growth signals. When these molecules were applied to bowel cancer cells, hundreds of cancer-related genes changed activity. The discovery helps explain how exercise lowers cancer risk and hints at future therapies inspired by movement.

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Scientists find exercise rivals therapy for depression

A large review of studies suggests that exercise can ease depression about as effectively as psychological therapy. Compared with antidepressants, exercise showed similar benefits, though the evidence was less certain. Researchers found that light to moderate activity over multiple sessions worked best, with few side effects. While it’s not a cure-all, exercise may be a powerful and accessible tool for many people.

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This brain trick makes exercise feel easier

Exercise doesn’t just challenge the body; it challenges how the brain interprets effort. Scientists discovered that vibrating tendons before cycling allowed people to push harder without feeling like they were working more. Their muscles and hearts worked overtime, but their sense of strain stayed the same. This brain-body mismatch could one day help make exercise feel less intimidating, especially for people who struggle to stay active.

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Magnetic nanoparticles fight bone cancer and help healing

Researchers have developed a magnetic nanomaterial that can kill bone cancer cells and support bone regeneration at the same time. The material heats up under a magnetic field to destroy tumors, while its bioactive coating helps it bond to bone and stimulate healing. Tests showed rapid formation of bone-like minerals, a key sign of successful integration. The breakthrough could lead to smarter, less invasive treatments for bone tumors.

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The simplest way teens can protect their mental health

Teens who sleep in on weekends may be giving their mental health a boost. A new study found that young people who made up for lost weekday sleep had a significantly lower risk of depression. While consistent sleep is still best, weekend catch-up sleep appears to offer meaningful protection. The findings highlight how powerful sleep can be for adolescent well-being.

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Harmful mouth bacteria may trigger Parkinson’s disease

A familiar mouth bacterium best known for causing cavities may also be quietly influencing the brain. Scientists found that when this microbe settles in the gut, it produces compounds that can travel through the bloodstream and harm neurons involved in movement. In animal studies, this process triggered inflammation, motor problems, and brain changes linked to Parkinson’s disease. The findings hint that protecting oral and gut health could help protect the brain as well.

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Scientists find a safer way for opioids to relieve pain

Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief without intensifying dangerous side effects like suppressed breathing. This research offers a fresh blueprint for designing opioids that last longer, work better, and pose fewer risks. It also opens doors to safer treatments for other brain disorders.

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Scientists uncover a hidden switch that helps cancer cells thrive

A protein once thought to simply help cancer cells avoid death turns out to do much more. MCL1 actively drives cancer metabolism by controlling the powerful mTOR growth pathway, tying survival and energy use together. This insight explains why MCL1-targeting drugs can be effective—but also why they sometimes damage the heart. Researchers have now identified a way to reduce that risk, potentially unlocking safer cancer therapies.

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Scientists find a safer way to make cells burn more calories

Researchers have developed experimental compounds that make cells burn more calories by subtly tweaking how mitochondria produce energy. Older versions of these chemicals were once used for weight loss—but were banned for being deadly. The new approach fine-tunes the effect, allowing cells to burn extra fuel safely. If successful, this could pave the way for new obesity treatments with added health benefits.

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Why warm hugs feel so good to your brain

Feeling warm or cold doesn’t just register on the skin—it changes how connected we feel to our own bodies. Research shows that temperature sensations help shape body ownership, emotional regulation, and mental well-being. Disruptions in thermal perception are linked to conditions like depression, trauma, and stroke-related body disconnect. These insights could lead to new sensory-based mental health treatments and more lifelike prosthetics.

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The invisible microbes that help keep us healthy

Not all microbes are villains—many are vital to keeping us healthy. Researchers have created a world-first database that tracks beneficial bacteria and natural compounds linked to immune strength, stress reduction, and resilience. The findings challenge the long-standing obsession with germs as threats and instead highlight the hidden health benefits of biodiversity. This shift could influence everything from urban design to environmental restoration.

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Menopause symptoms are common even in elite endurance athletes

Menopause symptoms are common among female endurance athletes and often interfere with training and performance. A survey of women aged 40–60 who train regularly found high rates of sleep problems, exhaustion, anxiety, weight gain, and joint pain. Many athletes said these symptoms made it harder to train effectively or perform at their best. The results highlight a need for greater attention to menopause in active women.

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A "herculean" genetic study just found a new way to treat ADHD

Attention depends on the brain’s ability to filter out distractions, but new research suggests this works best when background brain activity is quieter. Scientists found that lowering certain versions of the Homer1 gene improved focus in mice by calming neural noise. The effect was strongest during a critical developmental window. This approach could inspire new treatments for ADHD that work by reducing mental clutter instead of increasing stimulation.

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This tiny nerve may help keep the heart young

A new study suggests the vagus nerve may be one of the heart’s most important defenders against aging. Researchers found that keeping this nerve connected to the heart helps protect heart cells and maintain strong pumping ability. Even partial restoration of the nerve was enough to slow harmful changes in heart tissue. The discovery could reshape future heart and transplant surgeries.

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A key Alzheimer’s gene emerges in African American brain study

Scientists studying Alzheimer’s in African Americans have uncovered a striking genetic clue that may cut across racial lines. In brain tissue from more than 200 donors, the gene ADAMTS2 was significantly more active in people with Alzheimer’s than in those without it. Even more surprising, this same gene topped the list in an independent study of White individuals. The discovery hints at a common biological pathway behind Alzheimer’s and opens the door to new treatment strategies.

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This 100-year-old teaching method is beating modern preschools

A first-of-its-kind national trial shows that public Montessori preschool students enter kindergarten with stronger reading, memory, and executive function skills than their peers. These gains don’t fade — they grow over time, bucking a long-standing trend in early education research. Even better, Montessori programs cost about $13,000 less per child than traditional preschool. The results suggest a powerful, affordable model hiding in plain sight.

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