In pancreatic cancer, a race against time

Scientists have found a way to 'intercept' pancreatic cancer. By inhibiting the cancer gene FGFR2, they were able to slow tumor formation. By targeting the FGFR2 and EGFR proteins, they were able to prevent pancreatic cancer from forming in the first place.

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Balance between two competing nerve proteins deters symptoms of autism in mice

In mice, autism symptoms arise when a certain pair of competing nerve proteins falls out of equilibrium, according to a new study.

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New flexible hydrogel could improve drug delivery for post-traumatic osteoarthritis treatment

Post-traumatic osteoarthritis (PTOA) is a condition that affects joints after an injury. Current treatments focus on relieving symptoms but do not prevent or stop the progression of the condition. Although emerging therapies have shown promise in preclinical studies, a major obstacle is delivering these therapies effectively into the joint, a highly dynamic environment subjected to constant mechanical stress. Researchers have created a new hydrogel to improve drug delivery for treating PTOA.

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Patient navigators improve colonoscopy rates after abnormal stool tests, study shows

Timely follow-up colonoscopies can reduce the mortality rate from colorectal cancer, and patient navigators can play an important role in facilitating screening.

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Awareness grows of cancer risk from alcohol consumption

Public awareness of the link between drinking alcohol and an elevated risk of cancer has grown since last fall, with 55% of U.S. adults saying that regularly consuming alcohol increases your chances of later developing cancer, according to a new survey.

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New options for controlling type 2 diabetes

Nearly 40% of patients diagnosed with type 2 diabetes imperil their health by stopping their medication within the first year, diabetes experts warn.

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New study validates lower limits of human heat tolerance

Human thermoregulation limits are lower than previously thought, indicating that some regions may soon experience heat and humidity levels exceeding safe limits for survival. The study underscores the urgent need to address climate change impacts on human health, providing vital data to inform public health strategies and climate models.

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Digital technology and AI can support workers with dementia

People with dementia can enjoy productive and rewarding working lives in the digital era, contrary to the widespread stereotype that dementia is incompatible with the use of modern technology, according to new research.

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Digital PCR can reliably determine if chronic myeloid leukemia patients in remission can successfully discontinue drug treatment

Researchers have found that the clinical application of BCR::ABL1 digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia (CML), which will help to determine for which patients chronic drug treatment could potentially be discontinued. This transcript that is unique for CML is more sensitive and accurate than the current standard, real-time quantitative PCR (RT-qPCR), for detecting ultralow levels of residual leukemic disease.

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Blue pigment improves foundation makeup shades for dark skin

Drugstores and makeup counters carry foundations in various olive, ivory and fair shades. But for people with darker skin tones, finding the right foundation shade can be a challenge. The darker foundations that exist often fall flat, appearing gray-like once applied on the skin. But now, researchers report a blue cosmetic color additive that gives darker foundations the warmth and depth that current foundations lack.

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