Study shows effectiveness of method to stem nearsightedness

A new report shows the benefit of wearing contact lenses for slowing myopia has a lasting effect -- good news since 50% of the world (5 billion people) will likely be nearsighted by 2050.

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Continuous glucose monitor data predicts type 1 diabetes complications

Data from continuous glucose monitors can predict nerve, eye and kidney damage caused by type 1 diabetes researchers have found. That suggests doctors may be able to use data from the devices to help save patients from blindness, diabetic neuropathy and other life-changing diabetes complications.

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MRI scanning and biopsy could reduce delays in the correct treatment for bladder cancer by more than six weeks

Patients with a common aggressive type of bladder cancer could get correct treatment significantly quicker as new research suggests that initial MRI imaging and biopsy could be used to reduce the time patients wait.

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Scientists identify new epigenetic approach to target colorectal cancer

A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells and potentially could be used to treat solid tumors, according to a new study.

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Three drug cocktail shows potential to boost CAR-T cancer therapy

Researchers have discovered a three-drug combination that enhances the generation of CAR-T cells, a type of cancer immunotherapy, and could improve CAR-T cell production for clinical treatments. The study emphasizes the importance of T-memory stem cells (TSCM) linked to stronger and more lasting cancer responses. The findings demonstrate the advantages of pharmacological approaches over genetic approaches to enrich TSCM-like cells as most gene-targeted therapies have not proven to be very effective in this arena.

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Study uses design features of the ICU to evaluate delirium

ICU delirium can be associated with a multitude of factors including underlying and acute medical conditions, pharmacologic agents or treatment regimens like surgery. Currently there is no definitive consensus on drug interventions that aid in the prevention of delirium or its treatment. While there has been some evidence that the ICU environment plays a role in delirium, more research is needed to understand this association. Researchers found windowed patient rooms were associated with an increase in the odds of developing delirium, when compared to patient rooms without windows.

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Uncurling a single DNA molecule and gluing it down helps sharpen images

Using advanced imaging techniques and precise microfluidics control to stretch out curly DNA into a straight line, new research demonstrates techniques for stretching and immobilizing DNA with minimum thermal fluctuation to enable detailed analysis. A team at Nagoya University experimented with ways to uncurl a DNA molecule using pressure applied to liquid flowing in a channel, with the pressure flow providing shear force that uncurled the DNA molecule. They found that controlling the flow velocity of the liquid helps fine-tune the shear force applied and allows precise adjustments of the stretch ratio of the DNA.

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Global study pinpoints genes for depression across ethnicities

New genetic risk factors for depression have been identified across all major global populations for the first time, allowing scientists to predict risk of depression regardless of ethnicity. The world's largest and most diverse genetic study ever into major depression has revealed nearly 300 previously unknown genetic links to the condition, experts say.

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United States dementia cases estimated to double by 2060

A new study shows that the risk of developing dementia anytime after age 55 among Americans is 42%, more than double the risk reported by older studies.

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DNA nanorobots can alter artificial cells

Scientists have succeeded in controlling the structure and function of biological membranes with the help of 'DNA origami'. The system they developed may facilitate the transportation of large therapeutic loads into cells. This opens up a new way for the targeted administration of medication and other therapeutic interventions. Thus, a very valuable instrument can be added to the toolbox of synthetic biology.

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