Scientists uncover 3 key brain pathways linked to lasting depression relief

Researchers have uncovered three brain pathways linked to lasting improvements in people receiving deep brain stimulation for severe, treatment-resistant depression. They also discovered that patients who failed to improve after two years shared a striking pattern: insufficient stimulation of a crucial brain connection. The findings suggest that millimeters in electrode placement could make a major difference in treatment outcomes.

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Scientists tested 39 sweeteners and uncovered surprising gut effects

Scientists have discovered that many common sweeteners can interfere with gut bacteria, with some combinations involving medications producing surprisingly strong effects. One sweetener mixed with a widely prescribed antidepressant reduced beneficial bacteria and microbial diversity in laboratory experiments, raising new questions about potential effects on gut health and immunity.

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Scientists find a youth protein that helps aging brain cells act young again

Scientists have discovered that a protein linked to youth helps protect the brain’s immune cells from age-related decline. Restoring the protein in older mice improved the cells’ ability to clear debris and reduced signs of inflammation, raising hopes for future treatments targeting brain aging and Alzheimer’s disease.

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Scientists discover how deep sleep builds muscle, burns fat, and boosts the brain

Scientists have discovered a surprising two-way relationship between sleep and growth hormone, revealing how the brain carefully balances physical recovery with wakefulness. The findings could help explain why poor sleep harms metabolism and brain health, potentially opening the door to new treatments for sleep and neurological disorders.

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New drug reverses severe fatty liver disease by repairing the gut

Scientists have discovered that a potential new drug can reverse severe fatty liver disease in animal models by restoring gut health and blocking harmful substances from reaching the liver. The breakthrough could pave the way for new treatments for liver disease and potentially other serious conditions, including cardiovascular disease.

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Stanford’s new microscope reveals living cells like never before

Stanford scientists have developed a revolutionary microscope that reveals the hidden inner workings of living cells in real time, without the fluorescent labels that can interfere with observations. The breakthrough could provide new insights into cancer, infectious diseases, and how drugs interact with cells.

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Brain cells meant to protect us may be fueling cognitive decline

Scientists have uncovered a surprising cause of age-related cognitive decline involving brain cells previously thought to be entirely beneficial. As these cells become dysfunctional, they can produce abnormal amounts of myelin, disrupting nerve fibers and potentially contributing to worsening memory and thinking skills.

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A protein that fuels cancer could also be the key to fighting it

Scientists have discovered how to turn a protein that normally fuels cancer growth into a weapon against it. By activating PPARD in immune cells, researchers made them better at burning fat and attacking tumors, slowing or stopping cancer growth in laboratory experiments. The approach showed promise against colorectal, breast, and ovarian cancers, as well as melanoma.

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USC scientists discover how to create a never-ending supply of cancer-fighting cells

USC scientists have discovered a way to create a potentially renewable supply of genetically engineered immune cells that can attack cancer and strengthen the body's natural defenses. By growing and modifying immature immune cells rather than mature ones, researchers developed a system that can continuously produce tumor-fighting cells inside the body.

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Yale scientists discover how stress changes the brain to make memories stronger

Yale scientists have uncovered how the stress hormone cortisol helps the brain turn emotional experiences into stronger, longer-lasting memories. The discovery reveals that stress can reshape communication between brain networks involved in emotion and memory, potentially explaining why certain moments are so difficult to forget.

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