New brain stimulation approach could treat depression in just 5 days

A weeklong, high-intensity version of TMS may work nearly as well as the standard six-week treatment for depression. In a UCLA study, patients who received five sessions a day for five days experienced meaningful symptom relief comparable to those on the traditional schedule. Some who didn’t improve immediately showed strong gains weeks later. The findings hint at a faster, more accessible path to recovery.

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Alzheimer’s may begin with a silent drop in brain blood flow

Subtle changes in brain blood flow and oxygen use are closely linked to hallmark signs of Alzheimer’s, including amyloid plaques and memory-related brain shrinkage. Simple, noninvasive scans may one day help spot risk earlier—by looking at the brain’s vascular health, not just its plaques.

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Training harder could be rewiring your gut bacteria

Training harder may do more than build muscle—it could transform your gut. Researchers found that intense workouts change the balance of bacteria and important compounds in athletes’ digestive systems. When training loads dropped, diet quality slipped and digestion slowed, triggering different microbial shifts. These hidden changes might influence performance in ways scientists are only beginning to understand.

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Babies exposed to far more “forever chemicals” before birth than scientists knew

Babies born in the early 2000s were exposed in the womb to far more “forever chemicals” than researchers once realized, according to a new study. By using advanced chemical screening on umbilical cord blood, scientists detected 42 different PFAS compounds, including many that standard tests do not routinely check for. These long lasting chemicals are found in common products like nonstick cookware, food packaging, and stain resistant fabrics, and they can build up in the body over time.

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Simple blood test can forecast Alzheimer’s years before memory loss

Scientists have created a blood test that can estimate when Alzheimer’s symptoms are likely to begin. By measuring a protein called p-tau217, the model predicts symptom onset within roughly three to four years. The protein mirrors the silent buildup of amyloid and tau in the brain long before memory loss appears. This advance could speed up preventive drug trials and eventually guide personalized care.

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Frozen for 5,000 years, this ice cave bacterium resists modern antibiotics

Deep inside a Romanian ice cave, locked away in a 5,000-year-old layer of ice, scientists have uncovered a bacterium with a startling secret: it’s resistant to many modern antibiotics. Despite predating the antibiotic era, this cold-loving microbe carries more than 100 resistance-related genes and can survive drugs used today to treat serious infections like tuberculosis and UTIs.

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“Celtic curse” hotspots found in Scotland and Ireland with 1 in 54 at risk

Researchers have mapped the genetic risk of hemochromatosis across the UK and Ireland for the first time, uncovering striking hotspots in north-west Ireland and the Outer Hebrides. In some regions, around one in 60 people carry the high-risk gene variant linked to iron overload. The condition can take decades to surface but may lead to liver cancer and arthritis if untreated.

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Generative AI analyzes medical data faster than human research teams

Researchers tested whether generative AI could handle complex medical datasets as well as human experts. In some cases, the AI matched or outperformed teams that had spent months building prediction models. By generating usable analytical code from precise prompts, the systems dramatically reduced the time needed to process health data. The findings hint at a future where AI helps scientists move faster from data to discovery.

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Scientists reveal how exercise protects the brain from Alzheimer’s

Exercise may sharpen the mind by repairing the brain’s protective shield. Researchers found that physical activity prompts the liver to release an enzyme that removes a harmful protein causing the blood-brain barrier to become leaky with age. In older mice, dialing down this protein reduced inflammation and improved memory. The discovery points to a surprising body-to-brain pathway that could inspire new Alzheimer’s therapies.

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Scientists discover the body’s hidden “off switch” for inflammation

A new human study has uncovered how the body naturally turns off inflammation. Researchers found that fat-derived molecules called epoxy-oxylipins rein in immune cells that can otherwise drive chronic disease. Using a drug to boost these molecules reduced pain faster and lowered harmful inflammatory cells. The discovery could pave the way for safer treatments for arthritis, heart disease, and other inflammation-related conditions.

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