A gene mutation may trap the brain in the wrong reality in schizophrenia patients

A newly identified gene mutation may help explain why schizophrenia patients struggle to update their understanding of reality. The mutation disrupts a brain circuit involved in flexible decision-making, causing mice to stick with outdated choices even when conditions change. Researchers pinpointed the issue to a key thalamus–prefrontal cortex pathway. By reactivating this circuit, they were able to restore normal behavior—raising hope for future therapies.

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Breakthrough could protect the vision cells that let you see faces and colors

Scientists have taken a major step toward protecting the very cells that make sharp, colorful vision possible. By testing more than 2,700 compounds in thousands of lab-grown human retinal models, researchers uncovered several molecules that can shield cone photoreceptors—the cells responsible for reading, recognizing faces, and seeing color—from degeneration. They also identified a key protective mechanism involving casein kinase 1, offering a promising new target for treatment.

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Scientists discover “molecular shredder” that helps deadly parasite evade the immune system

A deadly parasite responsible for sleeping sickness has been found using a surprisingly precise trick to stay hidden in the human bloodstream. Scientists discovered a protein called ESB2 that acts like a “molecular shredder,” cutting up specific genetic instructions as they are produced. This allows the parasite to flood its surface with protective proteins while suppressing other signals that might give it away.

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This simple Japanese eating habit could help you live longer without dieting

Hara hachi bu, a traditional Japanese practice of eating until you’re about 80% full, is gaining attention as a simple yet powerful way to improve health and reshape our relationship with food. Rather than promoting strict dieting, it encourages slowing down, tuning into hunger cues, and eating with awareness and gratitude. Research suggests it may help reduce calorie intake, support healthier food choices, and prevent long-term weight gain.

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Eating more meat may lower Alzheimer’s risk for some people

A surprising new study suggests that genetics may change how diet affects brain health—especially when it comes to Alzheimer’s risk. Researchers found that older adults carrying high-risk APOE gene variants didn’t show the expected cognitive decline if they ate relatively high amounts of meat. In fact, those with these genes who consumed the most meat had slower cognitive decline and lower dementia risk, challenging conventional dietary advice.

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What’s hiding inside colon cancer could change treatment

Colorectal cancer may carry a unique microbial “fingerprint,” setting it apart from other cancers and opening a new frontier in diagnosis and treatment. By analyzing DNA from over 9,000 patients, researchers discovered that only colorectal tumors consistently host distinct microbial communities—challenging the long-held belief that all cancers have their own microbial signatures.

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Coffee at night may increase risky behavior, especially in women

Drinking coffee at night might come with an unexpected downside: increased impulsivity. In a new study, fruit flies given caffeine after dark behaved more recklessly, ignoring signals that normally make them stop. Daytime caffeine didn’t have the same effect, pointing to a strong link between timing and behavior. Even more striking, females were far more sensitive than males.

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Scientists discover hidden “winds” inside cells that could explain cancer spread

Cells aren’t as passive as scientists once thought—they actively create internal currents to move proteins quickly and efficiently. These “cellular winds” push materials to the front of the cell, enabling faster movement and repair. Discovered by chance and confirmed with advanced imaging, this system challenges decades of textbook biology. It may also reveal why some cancer cells spread so rapidly.

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Your DNA is constantly moving—and it may explain cancer

Scientists have uncovered a surprising secret about our DNA: it’s not a static blueprint, but a constantly shifting, folding structure that helps control how genes turn on and off. Researchers at the Salk Institute found that different parts of the genome loop and unloop at different speeds, with more active regions constantly reshaping themselves to support gene activity.

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Scientists discover sleep switch that builds muscle, burns fat, and boosts brainpower

Deep sleep does far more than rest the body — it activates a powerful brain-driven system that controls growth hormone, fueling muscle and bone strength, metabolism, and even mental performance. Scientists have now mapped the neural circuits behind this process, uncovering a delicate feedback loop in which sleep boosts growth hormone, and that same hormone helps regulate wakefulness.

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