Scientists discover a bacterial kill switch and it could change the fight against superbugs

Drug-resistant bacteria are becoming harder to treat, pushing scientists to look for new antibiotic targets. Researchers have now discovered that several unrelated viruses disable a key bacterial protein called MurJ, which is essential for building the bacterial cell wall. High-resolution imaging shows these viral proteins lock MurJ into a single position, stopping cell wall construction and leading to bacterial death.

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How the body really ages: 7 million cells mapped across 21 organs

Scientists have built a massive cellular atlas showing how aging reshapes the body across 21 organs. Studying nearly 7 million cells, they found that aging starts earlier than expected and unfolds in a coordinated way throughout the body. About a quarter of cell types change in number over time, and many of these shifts differ between males and females. The research also highlights shared genetic “hotspots” that could become targets for anti-aging therapies.

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Your morning coffee could one day help fight cancer

Scientists at Texas A&M are turning an everyday pick-me-up into a high-tech medical switch. By combining caffeine with CRISPR gene editing, researchers have created a system that allows cells to be programmed in advance — and then activated simply by consuming a small dose of caffeine from coffee, chocolate, or soda. The approach, known as chemogenetics, lets scientists precisely turn gene-editing activity on and off inside targeted cells, including powerful immune T cells that can fight cancer.

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Scientists discover diet that tricks the body into burning fat without exercise

Researchers found that cutting two amino acids common in animal protein—methionine and cysteine—made mice burn significantly more energy. The boost in heat production was nearly as powerful as constant exposure to cold temperatures. The mice didn’t eat less or exercise more; they simply generated more heat in their beige fat. The discovery hints that diet alone might activate the body’s calorie-burning machinery.

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American Heart Association warns 60% of US women will have cardiovascular disease by 2050

Heart disease is on track to tighten its grip on American women. New projections from the American Heart Association warn that over the next 25 years, cardiovascular disease will rise sharply, driven largely by a surge in high blood pressure, diabetes, and obesity. By 2050, nearly 60% of women in the U.S. could have high blood pressure, and close to one in three women ages 22 to 44 may already be living with some form of heart disease.

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Scientists discover hidden sugar layer behind psoriasis

A gel-like sugar coating on immune cells has been found to play a starring role in psoriasis. Researchers discovered that immune cells shed this outer layer to help them exit the bloodstream and enter inflamed skin. This challenges the long-held idea that only blood vessel walls changed during this process. The finding could help guide new therapies aimed at controlling harmful inflammation.

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New brain stimulation approach could treat depression in just 5 days

A weeklong, high-intensity version of TMS may work nearly as well as the standard six-week treatment for depression. In a UCLA study, patients who received five sessions a day for five days experienced meaningful symptom relief comparable to those on the traditional schedule. Some who didn’t improve immediately showed strong gains weeks later. The findings hint at a faster, more accessible path to recovery.

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Alzheimer’s may begin with a silent drop in brain blood flow

Subtle changes in brain blood flow and oxygen use are closely linked to hallmark signs of Alzheimer’s, including amyloid plaques and memory-related brain shrinkage. Simple, noninvasive scans may one day help spot risk earlier—by looking at the brain’s vascular health, not just its plaques.

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Training harder could be rewiring your gut bacteria

Training harder may do more than build muscle—it could transform your gut. Researchers found that intense workouts change the balance of bacteria and important compounds in athletes’ digestive systems. When training loads dropped, diet quality slipped and digestion slowed, triggering different microbial shifts. These hidden changes might influence performance in ways scientists are only beginning to understand.

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Babies exposed to far more “forever chemicals” before birth than scientists knew

Babies born in the early 2000s were exposed in the womb to far more “forever chemicals” than researchers once realized, according to a new study. By using advanced chemical screening on umbilical cord blood, scientists detected 42 different PFAS compounds, including many that standard tests do not routinely check for. These long lasting chemicals are found in common products like nonstick cookware, food packaging, and stain resistant fabrics, and they can build up in the body over time.

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