Inflammation and pressure-sensing leads to 'feed-forward' loop in osteoarthritis

An unfortunate biological 'feed-forward' loop drives cartilage cells in an arthritic joint to actually contribute to progression of the disease, say researchers. Excessive loading under inflammatory conditions can create a situation that can lead to progressive cartilage degeneration.

from Top Health News -- ScienceDaily https://ift.tt/392TbIb