Friday, November 29, 2024

Brain stimulation effectiveness tied to learning ability, not age

A study reveals that the effectiveness of brain stimulation on motor skills is determined by an individual's learning ability rather than age, highlighting the need for a more personalized approach to neurorehabilitation.

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First new treatment for asthma attacks in 50 years

A recent trial finds an injection given during some asthma and COPD attacks is more effective than the current treatment of steroid tablets, reducing the need for further treatment by 30%.

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Thursday, November 28, 2024

Nanorobot hand made of DNA grabs viruses for diagnostics and blocks cell entry

A tiny, four-fingered 'hand' folded from a single piece of DNA can pick up the virus that causes COVID-19 for highly sensitive rapid detection and can even block viral particles from entering cells to infect them, researchers report. Dubbed the NanoGripper, the nanorobotic hand also could be programmed to interact with other viruses or to recognize cell surface markers for targeted drug delivery, such as for cancer treatment.

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Wednesday, November 27, 2024

Tirzepatide shows powerful diabetes-prevention effect in three-year trial

Tirzepatide, a new injectable weight-loss drug, reduced the risk of diabetes in patients with obesity and prediabetes by more than 90% over a three-year period, compared with placebo, according to the results of a new study.

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Tuesday, November 26, 2024

Home testing kits and coordinated outreach substantially improve colorectal cancer screening rates

Colorectal cancer screening is an effective tool for catching the disease early when it's most treatable, yet it is underutilized at federally qualified health centers (FQHC). A new study demonstrated that a targeted intervention that paired mailing at-home colorectal cancer screening kits with coordinated follow-up tripled screening completion rates compared to usual care at FQHCs.

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Popular diabetes and obesity drugs also protect kidneys, study shows

The biggest and most comprehensive analysis of glucagon-like peptide-1 (GLP-1) receptor agonists on kidney and cardiovascular outcomes shows they have significant benefits in people with and without diabetes.

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Monday, November 25, 2024

Short-term menopausal hormone therapy has no long-term cognitive impact, study finds

Short-term menopausal hormone therapy (MHT) did not have long-term cognitive effects when given to women in early postmenopause, according to a new study.

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AI protein engineer capable of making proteins 'better, faster, stronger'

Engineered proteins are critical industrial and medical applications, ranging from vaccine development to making crops or food proteins more resilient. Scientists can engineer proteins to improve upon nature, but such experiments are time- and labor-intensive. Researchers have developed an AI-based protein design tool known as EVOLVEPro, which is already showing promise for several applications and could be used to help solve other medical challenges.

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Sunday, November 24, 2024

New technology points to unexpected uses for snoRNA

Researchers recently developed a new approach for identifying new cellular RNA targets of snoRNAs. They uncovered thousands of previously unknown targets for snoRNAs in human cells and mouse brain tissues, including many that serve functions other than guiding rRNA modifications.

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Friday, November 22, 2024

New imaging method enables detailed RNA analysis of the whole brain

Researchers have developed a groundbreaking microscopy method that enables detailed three-dimensional (3D) RNA analysis at cellular resolution in whole intact mouse brains. The new method, called TRISCO, has the potential to transform our understanding of brain function, both in normal conditions and in disease, according to the new study.

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From food crops to cancer clinics: Lessons in extermination resistance

Researchers explore how established agricultural pest management strategies could be adapted to address cancer therapy. The pioneering method opens new possibilities for controlling drug resistance and improving patient survival.

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Your child, the sophisticated language learner

Sentences contain subtle hints in their grammar that tell young children about the meaning of new words, according to new research.

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Confidence drives feedback-seeking behavior: Insights into learning and motivation

New research reveals how low confidence drives feedback-seeking, enhancing learning with insights for education and rehabilitation strategies.

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Thursday, November 21, 2024

Researchers use artificial intelligence to diagnose depression

Depression is one of the most common mental illnesses. As many as 280 million people worldwide are affected by this disease, which is why researchers have developed an artificial intelligence (AI) model that helps to identify depression based on both speech and brain neural activity. This multimodal approach, combining two different data sources, allows a more accurate and objective analysis of a person's emotional state, opening the door to a new phase of depression diagnosis.

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Wednesday, November 20, 2024

How children learned for 99% of human history

Unlike kids in the United States, hunter-gatherer children in the Congo Basin have often learned how to hunt, identify edible plants and care for babies by the tender age of six or seven. This rapid learning is facilitated by a unique social environment where cultural knowledge is passed down not just from parents but from the broader community. The research helps explain how many cultural traits have been preserved for thousands of years among hunter-gatherer groups across a wide range of natural environments in Africa.

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Spinning fusion fuel for efficiency

A new method to increase fusion-fuel efficiency would involve aligning the quantum spin of deuterium and tritium and changing the mix of the two fuels. The approach could boost tritium-burn efficiency by up to 10 times, reducing tritium needs and lowering fusion system costs. The technique could lead to safer, more compact fusion systems, making fusion energy more practical and affordable.

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Earlier diabetes diagnosis linked to dementia risk

People diagnosed with type 2 diabetes at a younger age are at a higher risk for developing dementia than those diagnosed later in life, according to a new study. The findings show that the increased risk is especially pronounced among adults with obesity.

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How jetlag can disrupt our metabolism

Have you ever felt sluggish and out of sorts after a long-haul flight or a late-night shift? A new study has found that disruptions to our body clock, such as those experienced during jetlag, impact our metabolism -- but to a lesser extent than sleepiness and the primary clock in the brain.

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Tuesday, November 19, 2024

Confinement may affect how we smell and feel about food

New research found confined and isolating environments changed the way people smelled and responded emotionally to certain food aromas. The team in this study compared 44 people's emotional responses and perception of eight food aromas in two environmental scenarios: sitting in reclined chairs that mimic astronauts' posture in microgravity; and then in the confined setting of the International Space Station (ISS), which was simulated for participants with virtual reality goggles. The research builds on previous work by the team and aims to help explain why astronauts report meals taste different in space and struggle to eat their normal nutritional intake over long missions, which has been reported in the news recently.

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Machine learning and supercomputer simulations help researchers to predict interactions between gold nanoparticles and blood proteins

Researchers have used machine learning and supercomputer simulations to investigate how tiny gold nanoparticles bind to blood proteins. The studies discovered that favorable nanoparticle-protein interactions can be predicted from machine learning models that are trained from atom-scale molecular dynamics simulations. The new methodology opens ways to simulate efficacy of gold nanoparticles as targeted drug delivery systems in precision nanomedicine.

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Monday, November 18, 2024

How optogenetics can put the brakes on epilepsy seizures

In what could one day become a new treatment for epilepsy, researchers have used pulses of light to prevent seizure-like activity in neurons.

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Gaming for the good!

It turns out gaming is good for you! New research indicates massive multiplayer online gamers learn by gaming and their skills in the workplace are enriched by those seemingly endless hours previously thought of as frittering away time.

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Sunday, November 17, 2024

Climate change and eye maladies

Clinical visits by patients suffering ocular surface eye conditions more than doubled during times when ambient particulate matter from air pollution was in the atmosphere, signaling a possible association between climate change and ocular health, according to a new study.

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Saturday, November 16, 2024

Achilles heel of antibiotic-resistant bacteria

To stem the surging antibiotic resistance public health crisis, scientists seek solutions inside the mechanics of bacterial infection. A new study has found a vulnerability related to magnesium availability. This limitation potentially could be exploited to stop the spread of antibiotic resistance.

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Traditional Mayan practices have long promoted unique levels of family harmony: But what effect is globalization having?

A new study shows that the past 30 years of globalization have brought fundamental shifts in some aspects of family interaction among Indigenous people in Guatemala. But families have still maintained a unique level of harmony in their interactions.

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Friday, November 15, 2024

Drug combination prompts immune response in some resistant pancreatic cancers

A new drug strategy that regulates the tumor immune microenvironment may transform a tumor that resists immunotherapy into a susceptible one, according to a new study.

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Thursday, November 14, 2024

Key influenza-severity risk factor found hiding in plain sight on our antibodies

Why do some people develop severe flu symptoms? A study points the finger at an unsung portion of the antibodies our immune systems generate to fend off invading pathogens.

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Wednesday, November 13, 2024

Lab-grown human immune system uncovers weakened response in cancer patients

These miniature immune system models -- known as human immune organoids -- mimic the real-life environment where immune cells learn to recognize and attack harmful invaders and respond to vaccines. Not only are these organoids powerful new tools for studying and observing immune function in cancer, their use is likely to accelerate vaccine development, better predict disease treatment response for patients, and even speed up clinical trials.

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Tuesday, November 12, 2024

Age-related health decline a predictor of future dementia risk

A new study has found frailty increases a person's risk of dementia, but early intervention may be the key to prevention.

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Monday, November 11, 2024

Elite coaches see compassion as a path to better performance

The potential of using compassion as a tool in elite sport is high, both for the individual athlete and in terms of sporting results, a study involving high-performance coaches shows.

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Unraveling the power and influence of language

A choice was made to include each word in this sentence. Every message, even the most mundane, is crafted with a specific frame in mind that...