This brain circuit may explain fluctuating sensations—and autism

Sometimes a gentle touch feels sharp and distinct, other times it fades into the background. This inconsistency isn’t just mood—it’s biology. Scientists found that the thalamus doesn’t just relay sensory signals—it fine-tunes how the brain responds to them, effectively changing what we feel. A hidden receptor in the cortex seems to prime neurons, making them more sensitive to touch.

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This tiny lung-on-a-chip could predict—and fight—the next pandemic

Scientists at Kyoto University have developed a groundbreaking "lung-on-a-chip" that can mimic the distinct regions of human lungs—airways and alveoli—to study how viruses like COVID-19 affect them differently. Powered by isogenic induced pluripotent stem cells (iPSCs), the system offers a high-fidelity way to model personalized immune responses and test drug effectiveness. This innovation opens the door to precision medicine, deeper understanding of emerging viruses, and even modeling of other organs in the future.

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Columbia scientists turn yogurt into a healing gel that mimics human tissue

Scientists at Columbia Engineering have developed an injectable hydrogel made from yogurt-derived extracellular vesicles (EVs) that could revolutionize regenerative medicine. These EVs serve both as healing agents and as structural components, eliminating the need for added chemicals. The innovation leverages everyday dairy products like yogurt to create a biocompatible material that mimics natural tissue and enhances healing.

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This gut hormone could explain 40% of IBS-D cases—and lead to a cure

A mysterious gut hormone may be behind many cases of chronic diarrhea, especially in people with undiagnosed bile acid malabsorption, a condition often mistaken for irritable bowel syndrome. Researchers from the University of Cambridge identified that the hormone INSL5 spikes when bile acid reaches the colon, triggering intense diarrhea. Their discovery not only sheds light on the biological cause of symptoms but opens the door to a diagnostic blood test and new treatment options, including a surprising existing drug that blocks this hormone’s effects.

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Can AI predict cancer? New model uses genomics to simulate tumors

A team of scientists has developed a remarkable new approach to modeling how cells behave over time—using a digital "forecast" much like predicting the weather. By combining patient genomics with a groundbreaking plain-language “hypothesis grammar,” the researchers can simulate how cells communicate and evolve within tissues. These simulations allow scientists to digitally test how cancers grow, how immune systems respond, and even how treatments might work in individual patients.

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COVID vaccines saved 2. 5M lives globally—a death averted per 5,400 shots

Between 2020 and 2024, COVID-19 vaccines saved 2.5 million lives globally, preventing one death for every 5,400 doses. A groundbreaking worldwide study led by researchers from Università Cattolica and Stanford University reveals that most lives were saved before individuals were exposed to the virus, particularly during the Omicron period and among those aged 60+. The researchers also calculated 14.8 million years of life saved, with the elderly gaining the majority of these benefits.

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Scientists discover the receptor that helps your brain clean itself—and fight Alzheimer’s

Scientists at UCSF have uncovered how certain immune cells in the brain, called microglia, can effectively digest toxic amyloid beta plaques that cause Alzheimer’s. They identified a key receptor, ADGRG1, that enables this protective action. When microglia lack this receptor, plaque builds up quickly, causing memory loss and brain damage. But when the receptor is present, it seems to help keep Alzheimer's symptoms mild. Since ADGRG1 belongs to a drug-friendly family of receptors, this opens the door to future therapies that could enhance brain immunity and protect against Alzheimer’s in more people.

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Scientists just invented a safer non-stick coating—and it’s inspired by arrows

Scientists at the University of Toronto have developed a new non-stick material that rivals the performance of traditional PFAS-based coatings while using only minimal amounts of these controversial "forever chemicals." Through an inventive process called "nanoscale fletching," they modified silicone-based polymers to repel both water and oil effectively. This breakthrough could pave the way for safer cookware, fabrics, and other products without the environmental and health risks linked to long-chain PFAS.

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7000 steps a day cuts death risk by 47%—and that might be all you need

Walking 7000 steps a day may be just as powerful as hitting the much-hyped 10,000-step goal when it comes to reducing the risk of early death and disease. A sweeping global review of 57 studies shows that 7000 steps per day slashes the risk of dying early by nearly half—and brings major benefits across heart health, dementia, depression, and more. The bonus? Even walking from 2000 to 4000 steps per day brings measurable improvements. For millions of people, this study redefines what it means to "move enough."

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Ivermectin: The mosquito-killing pill that dropped malaria by 26%

A groundbreaking study has revealed that the mass administration of ivermectin—a drug once known for treating river blindness and scabies—can significantly reduce malaria transmission when used in conjunction with bed nets.

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This DNA test can predict if a 5-year-old will be obese as an adult

What if we could predict obesity before it ever takes hold? A global team has created a genetic test that forecasts a child’s risk of adult obesity before age five—years before other factors kick in. By analyzing data from over five million people, their polygenic risk score doubles the predictive power of previous tools. While genetics isn’t destiny, those with higher genetic risk respond better to weight loss interventions but may regain weight quickly. The tool isn’t perfect, it performs far better in people of European ancestry, but it’s a game-changer in early prevention.

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Millipedes make ants dizzy — and might soon treat human pain

Millipedes, often dismissed as creepy crawlies, may hold the secret to future painkillers and neurological drugs. Researchers at Virginia Tech discovered unique alkaloid compounds in the defensive secretions of a native millipede species. These complex molecules, which cause disorientation in ants, interact with human neuroreceptors linked to pain and cognition. By decoding these natural chemical defenses, scientists could open a new path toward innovative drug therapies, though challenges remain in producing the compounds at scale.

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The plant virus that trains your immune system to kill cancer

A virus from humble black-eyed peas is showing extraordinary promise in the fight against cancer. Unlike other plant viruses, the cowpea mosaic virus (CPMV) can awaken the human immune system and transform it into a cancer-fighting powerhouse, without infecting human cells. By comparing it to a similar, but ineffective, virus, researchers uncovered that CPMV uniquely triggers potent interferons and immune responses, making it a low-cost, plant-grown immunotherapy on the fast track toward clinical trials.

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Your brain sees faces in everything—and science just explained why

You may be seeing faces in clouds, toast, or cars—and it turns out your brain is wired to notice them. A fascinating new study shows how our attention is hijacked not just by real faces, but by face-like illusions, through entirely different mental mechanisms. These imaginary expressions actually spark a stronger response, and the research even hints at clever ways advertisers could use this effect to grab your attention.

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Scientists just resurrected the 1918 “Spanish Flu” virus—here’s what they found

Scientists in Switzerland have cracked open a century-old viral mystery by decoding the genome of the 1918 influenza virus from a preserved Zurich patient. This ancient RNA revealed that the virus had already adapted to humans at the very start of the pandemic, carrying mutations that made it both more infectious and more immune-resistant. By pioneering a new method to recover fragile RNA from preserved tissue, researchers gained rare insights into how flu viruses evolve. The study not only revives the history of one of humanity's deadliest outbreaks but also arms us with critical knowledge to face future pandemics with smarter, science-based strategies.

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A simple twist fooled AI—and revealed a dangerous flaw in medical ethics

Even the most powerful AI models, including ChatGPT, can make surprisingly basic errors when navigating ethical medical decisions, a new study reveals. Researchers tweaked familiar ethical dilemmas and discovered that AI often defaulted to intuitive but incorrect responses—sometimes ignoring updated facts. The findings raise serious concerns about using AI for high-stakes health decisions and underscore the need for human oversight, especially when ethical nuance or emotional intelligence is involved.

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Just two workouts a week could cut heart death risk by 33% in diabetics

Even if you're cramming your workouts into the weekend, you might be doing your heart a big favor—especially if you have diabetes. A large study of over 50,000 adults with diabetes found that both “weekend warriors” and those who spread out their exercise during the week saw significant reductions in all-cause and cardiovascular mortality risks. Surprisingly, the pattern of exercise didn’t matter as long as the total time met current health guidelines. That means squeezing in your 150 minutes of moderate-to-vigorous physical activity over one or two days can be just as beneficial as spreading it out over several sessions.

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Cancer cells go up in flames—thanks to this deep-sea sugar

Scientists have discovered a sugar compound from deep-sea bacteria that can destroy cancer cells in a dramatic way. This natural substance, produced by microbes living in the ocean, causes cancer cells to undergo a fiery form of cell death, essentially making them self-destruct. In lab tests and in mice with liver cancer, the compound not only stopped tumors from growing, but also activated the immune system to fight back. This finding could pave the way for entirely new cancer treatments based on sugars from marine organisms.

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New genetic test predicts obesity before you start kindergarten

A groundbreaking study involving genetic data from over five million people has uncovered how our DNA can predict obesity risk as early as childhood. The new polygenic risk score outperforms previous methods, helping to identify high-risk children before weight issues develop paving the way for early lifestyle interventions.

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Magic mushrooms rewind aging in mice—could they do the same for humans?

A surprising discovery from Emory University shows that psilocin, the active metabolite of psychedelic mushrooms, can delay cellular aging and extend lifespan. Human cells lived over 50% longer, and mice treated with psilocybin not only lived 30% longer but also looked and aged better.

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Scientists just discovered a secret code hidden in your DNA

What scientists once dismissed as junk DNA may actually be some of the most powerful code in our genome. A new international study reveals that ancient viral DNA buried in our genes plays an active role in controlling how other genes are turned on or off, especially during early human development. These sequences, originally from long-extinct viruses, have evolved to act like tiny genetic switches. Using new analysis tools and large-scale experiments, researchers discovered that certain viral DNA fragments are especially strong at activating genes and may even have helped shape what makes humans different from other primates.

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A tiny chemistry hack just made mRNA vaccines safer, stronger, and smarter

What if mRNA vaccines could be made more powerful and less irritating? Scientists at the University of Pennsylvania have found a way to do just that—by tweaking a key molecule in the vaccine’s delivery system. Using a century-old chemical trick called the Mannich reaction, they added anti-inflammatory phenol groups to the lipids that carry mRNA into cells. The result? A new class of lipids that reduce side effects, boost gene-editing success, fight cancer more effectively, and supercharge vaccines like those for COVID-19. This breakthrough could change how we build the next generation of vaccines and therapies.

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New Duke study finds obesity rises with caloric intake, not couch time

People in richer countries aren’t moving less — they’re just eating more. A new Duke study shows that diet, not laziness, is fueling the obesity epidemic across industrialized nations.

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Doctors used music instead of medication—what they saw in dementia patients was remarkable

A groundbreaking pilot in NHS dementia wards is using live music therapy—called MELODIC—to ease patient distress without relying on drugs. Developed by researchers and clinicians with input from patients and families, this low-cost approach embeds music therapists directly into care teams. Early results show improved patient wellbeing and less disruptive behavior, sparking hope for wider NHS adoption.

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Not just hot flashes: The hidden depression crisis in early menopause

Premature menopause isn t just a hormonal issue it s a deeply emotional one for many women. A new study reveals that almost 30% experience depression, and it s not just about hormone loss but also grief, identity, and support systems.

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It’s not that you look—it’s when: The hidden power of eye contact

A groundbreaking study from Flinders University reveals that it's not just making eye contact that matters, but precisely when and how you do it. By studying interactions between humans and virtual partners, researchers discovered a powerful gaze sequence that makes people more likely to interpret a look as a call for help. Even more surprising: the same response pattern held true whether the "partner" was human or robot, offering insights into how our brains instinctively process social cues.

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1,000-year-old health hacks are trending—and backed by science

Medieval medicine is undergoing a reputation makeover. New research reveals that far from being stuck in superstition, early Europeans actively explored healing practices based on nature, observation, and practical experience—some of which uncannily echo today’s wellness trends on TikTok.

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Six-hour ‘undo’ button: GAI-17 rewinds stroke damage and may beat Alzheimer’s

Stroke kills millions, but Osaka researchers have unveiled GAI-17, a drug that halts toxic GAPDH clumping, slashes brain damage and paralysis in mice—even when given six hours post-stroke—and shows no major side effects, hinting at a single therapy that could also tackle Alzheimer’s and other tough neurological disorders.

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Obesity is driving a hidden cancer epidemic—13 types and rising deaths nationwide

Obesity-related cancer deaths in the U.S. have tripled in just two decades, with women, older adults, and minority groups most affected. New research presented at ENDO 2025 highlights how obesity—linked to 13 different cancers—is now a major contributor to cancer mortality, especially in underserved and rural populations. Despite the growing awareness of obesity’s broader health impacts, this surge in cancer fatalities reveals an urgent need for targeted public health interventions and equitable access to care.

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Sweet but risky: Common sweeteners may be accelerating puberty in kids

Kids who consume artificial and natural sweeteners like aspartame, sucralose, and glycyrrhizin may face an increased risk of early puberty, especially if they carry specific genetic markers. This large-scale Taiwanese study links sweeteners to hormonal changes and gut bacteria imbalances that can speed up puberty, with effects differing between boys and girls. Early onset puberty has been tied to serious health consequences later in life, including emotional stress and metabolic disorders. The findings could reshape dietary recommendations and encourage genetic screening to mitigate long-term risks.

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Deadly disguise: How candy-like nicotine pouches caused a 763% spike in child poisonings

A massive spike in young children accidentally ingesting nicotine pouches has alarmed poison control researchers, with a 763% rise reported between 2020 and 2023. Unlike other nicotine products, these pouches have quickly become the most dangerous form ingested, often leading to hospital visits. Experts say appealing packaging and flavors are part of the problem and they're pushing for tougher safety measures, including childproof storage and flavor bans.

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Tirzepatide: The weight-loss drug that also shrinks breast tumors in mice

In a striking new study, the anti-obesity drug tirzepatide, known as Mounjaro and Zepbound, not only triggered significant weight loss in obese mice but also slashed breast cancer tumor growth. The research, presented at ENDO 2025, links body fat reduction to better cancer outcomes, suggesting that these next-generation weight-loss drugs might offer unexpected benefits beyond metabolic health. With traditional dieting often falling short, this dual-action approach could reshape how doctors tackle obesity-related cancers.

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Princeton study maps 200,000 years of Human–Neanderthal interbreeding

For centuries, we’ve imagined Neanderthals as distant cousins — a separate species that vanished long ago. But thanks to AI-powered genetic research, scientists have revealed a far more entangled history. Modern humans and Neanderthals didn’t just cross paths; they repeatedly interbred, shared genes, and even merged populations over nearly 250,000 years. These revelations suggest that Neanderthals never truly disappeared — they were absorbed. Their legacy lives on in our DNA, reshaping our understanding of what it means to be human.

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The first pandemic? Scientists find 214 ancient pathogens in prehistoric DNA

Scientists have uncovered DNA from 214 ancient pathogens in prehistoric humans, including the oldest known evidence of plague. The findings show zoonotic diseases began spreading around 6,500 years ago, likely triggered by farming and animal domestication. These ancient infections may still influence us today, and help guide the vaccines of tomorrow.

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This tiny implant could save diabetics from silent, deadly crashes

MIT engineers have developed a tiny implantable device that could revolutionize emergency treatment for people with Type 1 diabetes. The device contains a powdered form of glucagon and can be remotely triggered—either manually or automatically by a glucose monitor—to release the hormone when blood sugar drops too low. This offers a potentially life-saving safety net, especially during sleep or for young children.

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The sleep-heart link doctors are urging women over 45 to know

Midlife sleep habits may matter more than previously thought. A large study finds that poor sleep, alongside high blood pressure and nicotine use, sharply increases the risk of heart problems in menopausal women yet only 1 in 5 score well on overall heart health.

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Your Brain’s Hidden Defenses Against Alzheimer’s

Scientists at UCSF combined advanced brain-network modeling, genetics, and imaging to reveal how tau protein travels through neural highways and how certain genes either accelerate its toxic journey or shield brain regions from damage. Their extended Network Diffusion Model pinpoints four gene categories that govern vulnerability or resilience, reshaping our view of Alzheimer’s progression and spotlighting fresh therapeutic targets.

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Bigger crops, fewer nutrients: The hidden cost of climate change

Climate change is silently sapping the nutrients from our food. A pioneering study finds that rising CO2 and higher temperatures are not only reshaping how crops grow but are also degrading their nutritional value—especially in vital leafy greens like kale and spinach. This shift could spell trouble for global health, particularly in communities already facing nutritional stress. Researchers warn that while crops may grow faster, they may also become less nourishing, with fewer minerals, proteins, and antioxidants—raising concerns about obesity, weakened immunity, and chronic diseases.

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Doctors say we’ve been misled about weight and health

Losing weight isn’t always winning at health, say experts challenging the long-standing obsession with BMI and dieting. New evidence shows that most people with higher body weight can’t sustain long-term weight loss through lifestyle changes—and the pressure to do so may actually cause harm. From disordered eating to reinforced stigma, the consequences go beyond the physical. A growing movement urges doctors to shift away from the scale and toward personalized, compassionate care that values overall well-being, not just shrinking waistlines.

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Alzheimer’s doesn’t strike at random: These 4 early-warning patterns tell the story

UCLA scientists mined millions of electronic health records and uncovered four distinct “roadways” that funnel people toward Alzheimer’s—ranging from mental-health struggles to vascular troubles. Following these breadcrumb trails proved far better at predicting who will develop dementia than single risk factors. The findings hint that spotting—and halting—specific sequences early could rewrite how we prevent the disease.

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New research shows Monday stress is etched into your biology

Feeling jittery as the week kicks off isn’t just a mood—it leaves a biochemical footprint. Researchers tracked thousands of older adults and found those who dread Mondays carry elevated cortisol in their hair for months, a stress echo that may help explain the well-known Monday heart-attack spike. Even retirees aren’t spared, hinting that society’s calendar, not the workplace alone, wires Monday anxiety deep into the HPA axis and, ultimately, cardiovascular risk.

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The surprising link between hearing loss, loneliness, and lifespan

People who treat hearing loss with hearing aids or cochlear implants regain rich conversations, escape isolation, and may even protect their brains and lifespans—proof that better hearing translates into fuller living.

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A cholesterol secret inside ticks may halt Lyme disease spread

Scientists have discovered that the bacteria behind Lyme disease and anaplasmosis have a sneaky way of surviving inside ticks—they hijack the tick’s own cell functions to steal cholesterol they need to grow. By tapping into a built-in protein pathway, the bacteria keep themselves alive until they can infect a new host. The research opens the door to new methods of stopping these diseases before ticks ever get the chance to bite. A new web tool also reveals that this trick might be used by other blood-feeding bugs too.

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Sweet-smelling molecule halts therapy-resistant pancreatic cancer

A compound best known for giving almonds and apricots their aroma may be the key to defeating hard-to-kill cancer cells. Japanese researchers found that benzaldehyde can stop the shape-shifting ability of aggressive cancer cells, which lets them dodge treatments and spread. By targeting a specific protein interaction essential for cancer survival—without harming normal cells—benzaldehyde and its derivatives could form the basis of powerful new therapies, especially when combined with existing radiation or targeted treatments.

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Why anger cools after 50: Surprising findings from a new menopause study

Anger isn’t just a fleeting emotion—it plays a deeper role in women’s mental and physical health during midlife. A groundbreaking study tracking over 500 women aged 35 to 55 reveals that anger traits like outbursts and hostility tend to diminish with age and menopause progression. This shift could signal enhanced emotional regulation during and after the reproductive transition. Surprisingly, the only form of anger that remained steady was suppressed anger.

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Deafness reversed: Single injection brings hearing back within weeks

A cutting-edge gene therapy has significantly restored hearing in children and adults with congenital deafness, showing dramatic results just one month after a single injection. Researchers used a virus to deliver a healthy copy of the OTOF gene into the inner ear, improving auditory function across all ten participants in the study. The therapy worked best in young children but still benefited adults, with one 7-year-old girl regaining almost full hearing. Even more exciting: this is just the start, as scientists now aim to target other genes that cause more common forms of deafness.

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This sun-powered sponge pulls drinking water straight from the ocean

In a leap toward sustainable desalination, researchers have created a solar-powered sponge-like aerogel that turns seawater into drinkable water using just sunlight and a plastic cover. Unlike previous materials, this new 3D-printed aerogel maintains its efficiency at larger sizes, solving a key scalability issue. In outdoor tests, it produced clean water directly from the ocean without any electricity, pointing to a future of low-cost, energy-free freshwater production.

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Are lefties really more creative? 100 years of data say no

A sweeping review of more than a century’s research upends the popular notion that left-handers are naturally more creative. Cornell psychologist Daniel Casasanto’s team sifted nearly a thousand studies, ultimately finding no consistent advantage for lefties on standard divergent-thinking tests—and even a slight edge for right-handers in some. The myth appears to thrive on coincidence: left-handedness is rare and so is creative genius, plus lefties’ overrepresentation in art and music gets cherry-picked while other professions are ignored.

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Scientists just mapped how the body rejects pig organs—and how to stop it

Scientists have achieved an unprecedented look into how the human immune system attacks a transplanted pig kidney, using spatial molecular imaging to map immune activity down to the cellular level. They discovered early signs of rejection within 10 days and pinpointed key immune players—like macrophages—driving the response. Even more exciting: when targeted therapies were applied, the immune assault weakened. As U.S. clinical trials of pig kidney transplants begin, this breakthrough offers hope for overcoming the immune barrier that has long stood in the way of xenotransplantation.

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This virus infects millions—and we just discovered its secret weapon

Scientists have discovered a stealthy mechanism that cytomegalovirus (CMV)—the leading infectious cause of birth defects in the U.S.—uses to infiltrate blood vessel cells while evading immune detection. The virus forms a hidden protein complex that acts like a molecular “backdoor,” allowing it to bypass the immune system’s defenses. This newly identified pathway may explain why vaccine efforts have failed for decades and opens the door to targeted therapies that could finally prevent CMV-linked birth defects in newborns and protect vulnerable patients.

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