When cancer cells are physically squeezed, they mount an instant, high-energy defense by rushing mitochondria to the cell nucleus, unleashing a surge of ATP that fuels DNA repair and survival. This newly discovered mechanism, visualized in real time with advanced microscopy, shows mitochondria acting like emergency first responders rather than static power plants. The structures, called NAMs, were also identified in patient tumor biopsies, suggesting real-world relevance to cancer’s spread.
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