Monday, December 15, 2025

Stem cell pain sponge soaks up osteoarthritis joint pain and protects cartilage

SereNeuro Therapeutics revealed promising results for SN101, a first-in-class iPSC-derived therapy designed to treat chronic osteoarthritis pain while protecting joint tissue. Instead of blocking pain pathways, SN101 uses lab-grown nociceptors that act like sponges, soaking up inflammatory pain factors without sending pain signals. These cells also release regenerative molecules, offering disease-modifying potential that stands apart from traditional corticosteroids and single-target drugs like Nav1.8 inhibitors.

from Top Health News -- ScienceDaily https://ift.tt/zfJhb9T

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Old muscle stem cells can act young again but there’s a catch

Scientists at UCLA discovered a surprising reason aging muscles heal more slowly. In older muscle stem cells, a protein called NDRG1 builds ...